All episodes

Ep. 75: Nosocomial Infections of the central nervous system

Ep. 75: Nosocomial Infections of the central nervous system

14m 13s

Moderator: Johann Sellner (Mistelbach, Austria)

Guest: Tamuna Akhvlediani (Tbilisi, Georgia)

In this last episode on Infectious Diseases, Prof. Johann Sellner and Prof. Tamuna Akhvlediani explore nosocomial infections of the central nervous system (CNS). They cover the definition, common pathogens, and prevention methods like infection control and standardized surgery. Prof. Akhvlediani specifies prevalent CNS infections and addresses challenges in prevention and treatment, notably due to antimicrobial resistance. The conversation concludes with insights into treatment strategies, emphasizing the increasing challenge of antimicrobial resistance in healthcare-associated infections.

Ep. 74: EBV in the pathogenesis of multiple sclerosis

Ep. 74: EBV in the pathogenesis of multiple sclerosis

14m 29s

Moderator: Tamuna Akhvlediani (Tbilisi, Georgia)

Guest: Johann Sellner (Mistelbach, Austria)

In this week’s podcast hosted by Dr. Tamuna Akhvlediani, Prof. Johann Sellner discusses the connection between Epstein-Barr virus (EBV) and multiple sclerosis (MS). They explore the immune-mediated nature of MS, focusing on the impact of EBV and recent studies linking its infection to MS development. The episode delves into the controversies, hypotheses, and potential therapies related to EBV and MS, concluding with information on ongoing clinical trials and the influence of existing MS treatments on EBV.

Ep. 73: Neuroinfections in times of COVID-19

Ep. 73: Neuroinfections in times of COVID-19

17m 52s

Moderator: Tamuna Akhvlediani (Tbilisi, Georgia)

Guest: Johann Sellner (Mistelbach, Austria)

Dr. Tamuna Akhvlediani hosts Professor Johann Sellner in a podcast discussing the impact of COVID-19 on neuro infections. Professor Sellner covers global neuro infections, the decline during lockdowns, and the effectiveness of measures like face masks and vaccination. The episode emphasizes lessons learned, including insights into chronic neuro infection care disruptions and challenges, such as neuro-AIDS management during the pandemic. It concludes with findings from a study on how COVID-19 affected different neurological subspecialties.

Ep. 72: Outcome of neurological toxicities of immune checkpoint inhibitors and the effect of drug rechallenge

Ep. 72: Outcome of neurological toxicities of immune checkpoint inhibitors and the effect of drug rechallenge

14m 55s

Moderator: Yildiz Değirmenci (Istanbul, Turkey)

Guest: Antonio Farina (Florence, Italy)

This week, Dr. Yildiz Değirmenci and Dr. Antonio Farina discuss life-threatening neurological toxicities from immune checkpoint inhibitors. Dr. Farina highlights high fatality rates, long-term disabilities, and the urgency of early recognition and treatment. The episode explores management, including discontinuation and corticosteroids, and factors influencing outcomes. It touches on the association between adverse events and treatment response, resuming inhibitors, and stresses a multidisciplinary approach for informed decision-making. The conclusion emphasizes the importance of neurologists' awareness in addressing these rare yet significant neurological complications.

Ep. 71: Neurological complications from cancer immunotherapy

Ep. 71: Neurological complications from cancer immunotherapy

18m 51s

Moderator: Antonio Malvaso

Guest: Stefania Cuzzubbo

Dr. Antonio Malva hosts Dr. Stefania Cuzzubbo to discuss neurological complications from cancer immunotherapy. Dr. Cuzzubbo highlights immune-related adverse events, focusing on peripheral nervous system issues. The importance of early diagnosis using MRI, lumbar puncture, and nerve studies is emphasized. Treatment involves promptly stopping the drug and using steroids, with alternative therapies explored for steroid-refractory cases. Continued research in this evolving field is crucial.

Ep. 70: Paraneoplastic neurological syndromes: diagnosis and treatment

Ep. 70: Paraneoplastic neurological syndromes: diagnosis and treatment

17m 51s

Moderator: Antonio Malvaso (Pavia, Italy)
Guest: Alberto Vogrig (Udine, Italy)
In this episode of EAN Cast Weekly Neurology, Dr. Antonio Malvaso, a neurology resident, welcomes Dr. Alberto Vogrig, an international expert in the field of paraneoplastic neurological syndromes. They discuss the definition of these syndromes, emphasizing the causal relationship with cancer and their immune-mediated pathogenesis. They also talk about the revised diagnostic criteria and the importance of clinical diagnosis, laboratory techniques, and oncologic screening. The treatment for these syndromes includes immunosuppression, cancer therapy, and symptomatic treatment, tailored to the specific symptoms.

Ep. 69: A clinical approach to neurological symptoms of patients with cancer

Ep. 69: A clinical approach to neurological symptoms of patients with cancer

15m 11s

Moderator: Alberto Vogrig (Udine, Italy)

Guest: Giulia Berzero (Milan, Italy)

In this episode Dr. Alberto Vogrig is joined by Dr. Giulia Berzero to discuss the clinical approach to neurological symptoms in patients with cancer. She highlights the increasing occurrence of neurological complications in cancer patients due to improved survival rates and novel cancer treatments. Dr. Berzero emphasizes the importance of considering patient-related factors, tumor-related factors, and treatment modalities in assessing the risk of developing neurological symptoms. She also explains the signs that may prompt suspicion of brain metastasis and provides guidance on assessing and diagnosing CNS dissemination in cancer patients....

Ep. 68: Analysis of CIDP guidelines

Ep. 68: Analysis of CIDP guidelines

21m 43s

Moderator: Panagiotis Zis (Nicosia, Cyprus)

Guest: Peter Van den Bergh (Brussels, Belgium)

In this episode of the EAN Cast, Prof. Zis is joined by Prof. Van den Bergh to discuss the recently updated guidelines for diagnosing and treating Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP). The existing guidelines were last revised over a decade ago, and this new version aims to reflect the latest advancements in clinical and basic research. Prof. Van den Bergh highlights the common pitfalls in CIDP diagnosis and emphasizes the need for accurate diagnostic criteria.

The guidelines include flowcharts, tables, and criteria for different CIDP variants, as well...

Ep. 67: EAN and WFN Brain Health Initiatives

Ep. 67: EAN and WFN Brain Health Initiatives

23m 5s

Moderator: Thomas Berger (Vienna, Austria)

Guest: Wolfgang Grisold (Vienna, Austria)

In this podcast episode of EAN Cast, Professor Thomas Berger, Chair of the Department of Neurology at the Medical University in Vienna, and Professor Wolfgang Grisold, the current president of the World Federation of Neurology, discuss two important topics. First, they delve into the history and implementation of the World Health Organization's (WHO) Intersectoral Global Action Plan for epilepsy and other neurological disorders (ICAP). They emphasize that ICAP is a global effort to improve neurological services, and while epilepsy is a key focus, it covers various neurological disorders across countries,...

Ep. 66: Classification of peripheral neuropathies

Ep. 66: Classification of peripheral neuropathies

16m 26s

Moderator: Yıldız Değirmenci (Istanbul, Turkey)

Guest: Panagiotis Zis (Nicosia, Cyprus)

In this podcast episode Dr. Yıldız Değirmenci is joined by Dr. Panagiotis Zis to discuss peripheral neuropathies. Dr. Panagiotis Zis explains that peripheral neuropathy refers to diseases or disorders of the peripheral nerves, including mono neuropathies affecting single nerves and poly neuropathies affecting multiple nerves. The clinical symptoms of peripheral neuropathy vary depending on the type and degree of nerve fiber involvement, with symptoms ranging from pain and abnormal sensations to motor issues like muscle atrophy and cramps.

Dr. Zis emphasizes the importance of a thorough neurological examination in diagnosing...