All episodes

Ep. 82: Gene Mutations and Gene Variants

Ep. 82: Gene Mutations and Gene Variants

16m 57s

Moderator: Federica Montagnese (Munich, Germany)
Guest: Magda Mroczek (Basel, Switzerland)
In this podcast, Dr. Federica Montagnese interviews Dr. Magdalena Mroczek about gene mutations and variants in neuromuscular disorders, with a focus on muscular dystrophies. They discuss the impact of advanced technologies on genetic testing, highlighting the importance of clinical data and collaboration between clinicians and geneticists. The conversation touches on challenges in interpreting variants, the role of epigenetic factors, and initiatives to enhance access to genetic tools in low-income countries through international collaborations. The podcast underscores the dynamic nature of genetic diagnostics, emphasizing the importance of continuous research and education...

Ep. 81: Stroke and Cardiology: Not Only a Matter of Brain

Ep. 81: Stroke and Cardiology: Not Only a Matter of Brain

20m 59s

Moderator: Barbara Tettenborn (St.Gallen, Switzerland)

Guest: Matthias Endres (Berlin, Germany)

In this episode, Barbara Tettenborn interviews Professor Matthias Endres, professor and chair of Neurology at the Charité Hospital in Berlin. The conversation delves into the connection between stroke and cardiology. Endres introduces the concept of stroke-induced atrial fibrillation, distinguishing it from pre-existing AF. They discuss the stroke heart syndrome, underlining the increased risk of cardiac events post-stroke. Troponin elevation is highlighted as a crucial biomarker, and the role of insular lesions in the brain in the syndrome is explored. The podcast concludes by emphasizing the importance of an interdisciplinary approach...

Ep. 80: Rare Causes of Stroke

Ep. 80: Rare Causes of Stroke

21m 30s

Moderator: Benedetta Storti (Milan, Italy)

Guest: Anita Arsovska (Skopje, North Macedonia)

Benedetta Storti hosts Prof. Arsovska as they explore rare causes of strokes, covering conditions like cardiomyopathy, fibromuscular dysplasia, and immune-related factors. Arsovska stresses the significance of a comprehensive diagnostic approach, discussing specific features in tests and advocating for thorough investigations. The podcast addresses potential errors in diagnostic pathways and underscores the importance of biopsy in certain cases. Arsovska shares insights into tailored treatment options based on underlying conditions.

Ep. 79: Hidden Hazards: A Dive into Covert Cerebrovascular Disease

Ep. 79: Hidden Hazards: A Dive into Covert Cerebrovascular Disease

18m 22s

Moderator: Barbara Tettenborn (St. Gallen, Switzerland)

Guest: Thomas Meinel (Bern, Switzerland)

Thomas Meinel, a clinician scientist at the Burn Stroke Research Center in Switzerland, is hosted by Barbara Tettenborn as they discuss covert cerebrovascular disease. His research, particularly on strokes in patients on anticoagulation, is explored, highlighting the frequency and clinical implications of covert cerebrovascular lesions. Meinel emphasizes the current lack of clear evidence for managing these conditions. He also shares insights into ongoing studies that aim to connect epidemiological knowledge with clinical practices, encouraging neurologists to recognize and address covert cerebrovascular disease in patient care.

Ep. 78: Advocating for Brain Health

Ep. 78: Advocating for Brain Health

23m 57s

Moderator: Rolf Fronczek (Leiden, The Netherlands)

Guest: Matilde Leonardi (Milan, Italy)
Celebrate the end of the year with us with this special episode on Brain Health! Rolf Fronczek hosts Matilde Leonardi discussing her international neurology career and passion for Brain Health. She highlights the WHO Global Action Plan on epilepsy, stresses the increasing global burden of neurological diseases, and advocates for preventative measures. Leonardi details EAN's Brain Health Strategy, urging neurologists to advocate for brain health individually and nationally. Emphasizing a bio-psychosocial approach, she invites participation in EAN's leadership and advocacy training to contribute to shaping global brain health.

Ep. 77: 30th Anniversary of the European Journal of Neurology

Ep. 77: 30th Anniversary of the European Journal of Neurology

17m 54s

Moderator: Barbara Tettenborn (St. Gallen, Switzerland)

Guest: Didier Leys (Lille, France)

In this eanCast episode, Barbara Tettenborn interviews Didier Leys, Editor-in-Chief of the European Journal of Neurology, marking its 30th anniversary. Leys discusses the journal's evolution, challenges, and current impact factor of five. He outlines his daily editorial duties, stressing manuscript selection, ethical standards, and team management. Future plans include webinars, a history special issue, a virtual issue of top-cited articles, and video interviews with editors. He also encourages young researchers to submit, citing impact factor and submission delay importance. The episode closes with a glimpse into exciting 30th-anniversary initiatives.

Ep. 76: Neurological side effects and drug interactions of new antiviral drugs against SARS-CoV-2

Ep. 76: Neurological side effects and drug interactions of new antiviral drugs against SARS-CoV-2

15m 56s

Moderator: Johann Sellner (Mistelbach, Austria)

Guest: Tamuna Akhvlediani (Tbilisi, Georgia)

In this podcast episode, Prof. Johann Sellner interviews Prof. Tamuna Akhvlediani about the neurological aspects of new antiviral drugs for SARS-CoV-2. They discuss drugs like monoclonal antibodies, paxlovid, and remdesivir, emphasizing their mechanisms and potential applications beyond COVID-19. Prof. Akhvlediani details neurological side effects observed in trials and significant drug interactions, especially in chronic neurological patients. The episode closes with insights into managing these interactions in clinical practice.

Ep. 75: Nosocomial Infections of the central nervous system

Ep. 75: Nosocomial Infections of the central nervous system

14m 13s

Moderator: Johann Sellner (Mistelbach, Austria)

Guest: Tamuna Akhvlediani (Tbilisi, Georgia)

In this last episode on Infectious Diseases, Prof. Johann Sellner and Prof. Tamuna Akhvlediani explore nosocomial infections of the central nervous system (CNS). They cover the definition, common pathogens, and prevention methods like infection control and standardized surgery. Prof. Akhvlediani specifies prevalent CNS infections and addresses challenges in prevention and treatment, notably due to antimicrobial resistance. The conversation concludes with insights into treatment strategies, emphasizing the increasing challenge of antimicrobial resistance in healthcare-associated infections.

Ep. 74: EBV in the pathogenesis of multiple sclerosis

Ep. 74: EBV in the pathogenesis of multiple sclerosis

14m 29s

Moderator: Tamuna Akhvlediani (Tbilisi, Georgia)

Guest: Johann Sellner (Mistelbach, Austria)

In this week’s podcast hosted by Dr. Tamuna Akhvlediani, Prof. Johann Sellner discusses the connection between Epstein-Barr virus (EBV) and multiple sclerosis (MS). They explore the immune-mediated nature of MS, focusing on the impact of EBV and recent studies linking its infection to MS development. The episode delves into the controversies, hypotheses, and potential therapies related to EBV and MS, concluding with information on ongoing clinical trials and the influence of existing MS treatments on EBV.

Ep. 73: Neuroinfections in times of COVID-19

Ep. 73: Neuroinfections in times of COVID-19

17m 52s

Moderator: Tamuna Akhvlediani (Tbilisi, Georgia)

Guest: Johann Sellner (Mistelbach, Austria)

Dr. Tamuna Akhvlediani hosts Professor Johann Sellner in a podcast discussing the impact of COVID-19 on neuro infections. Professor Sellner covers global neuro infections, the decline during lockdowns, and the effectiveness of measures like face masks and vaccination. The episode emphasizes lessons learned, including insights into chronic neuro infection care disruptions and challenges, such as neuro-AIDS management during the pandemic. It concludes with findings from a study on how COVID-19 affected different neurological subspecialties.